%0 Journal Article %T Astaxanthin Supplemented with High-Intensity Functional Training Decreases Adipokines Levels and Cardiovascular Risk Factors in Men with Obesity %+ University of Kurdistan [Sanandaj - Iran] (UOK) %+ Urmia University %+ Razi University of Kermanshah %+ West Tehran Islamic Azad University [Tehran] (WTIAU) %+ Alzahra University %+ Ataturk University %+ Hakim Sabzevari University %+ Sultan Qaboos University (SQU) %+ University of North Carolina [Chapel Hill] (UNC) %+ University of British Columbia [Vancouver] %+ Kansas State University %+ Laboratoire Mouvement Sport Santé (M2S) %+ Institut International des Sciences du Sport (2I2S) %A Saeidi, Ayoub %A Nouri-Habashi, Akbar %A Razi, Omid %A Ataeinosrat, Ali %A Rahmani, Hiwa %A Mollabashi, Shirin Shirzad %A Bagherzadeh-Rahmani, Behnam %A Aghdam, Shahin Mahmoudi %A Khalajzadeh, Leila %A Al Kiyumi, Maisa Hamed %A Hackney, Anthony C. %A Laher, Ismail %A Heinrich, Katie M %A Zouhal, Hassane %Z None %< avec comité de lecture %@ 2072-6643 %J Nutrients %I MDPI %V 15 %N 2 %P 286 %8 2023-01-06 %D 2023 %R 10.3390/nu15020286 %M 36678157 %K adipokines %K astaxanthin %K cardiovascular risk factors %K high-intensity training %K obesity %Z Life Sciences [q-bio]Journal articles %X The aim of this study was to investigate the effects of 12 weeks of high-intensity training with astaxanthin supplementation on adipokine levels, insulin resistance and lipid profiles in males with obesity. Sixty-eight males with obesity were randomly stratified into four groups of seventeen subjects each: control group (CG), supplement group (SG), training group (TG), and training plus supplement group (TSG). Participants underwent 12 weeks of treatment with astaxanthin or placebo (20 mg/d capsule daily). The training protocol consisted of 36 sessions of high-intensity functional training (HIFT), 60 min/sessions, and three sessions/week. Metabolic profiles, body composition, anthropometrical measurements, cardio-respiratory indices and adipokine [Cq1/TNF-related protein 9 and 2 (CTRP9 and CTRP2) levels, and growth differentiation factors 8 and 15 (GDF8 and GDF15)] were measured. There were significant differences for all indicators between the groups (p andlt; 0.05). Post-hoc analysis indicated that the levels of CTRP9, CTRP2, and GDF8 were different from CG (p andlt; 0.05), although levels of GDF15 were similar to CG (p andgt; 0.05). Levels of GDF8 were similar in the SG and TG groups (p andgt; 0.05), with reductions of GDF15 levels in both training groups (p andlt; 0.05). A total of 12 weeks of astaxanthin supplementation and exercise training decreased adipokines levels, body composition (weight, %fat), anthropometrical factors (BMI), and improved lipid and metabolic profiles. These benefits were greater for men with obesity in the TSG group. %G English %2 https://hal.science/hal-03972192/document %2 https://hal.science/hal-03972192/file/nutrients-15-00286.pdf %L hal-03972192 %U https://hal.science/hal-03972192 %~ UNIV-BREST %~ UNIV-RENNES1 %~ UR2-HB %~ ENS-CACHAN %~ IFR140 %~ STATS-UR1 %~ M2S %~ UR1-HAL %~ UR1-SHS %~ UNIV-RENNES2 %~ TEST-UR-CSS %~ UNIV-RENNES %~ UR1-BIO-SA %~ ENS-PARIS-SACLAY